Formulation and Optimization of Matrix Tablets Based on Spirulina and Vitamin C
نویسندگان
چکیده
Spirulina is a type of algae widely consumed around the world as dietary supplement due to its great nutritional potential. However, it does not contain vitamin C, vital for proper functioning human body, particularly given immunostimulant The objective this work was formulate sustained release spirulina–vitamin C matrix tablets that would enhance prolonged and better absorption C. A galenic formula based only on made, then proportion reduced in favor spirulina powder. manufactured were subjected various pharmacopeial quality control tests. results these tests showed good distribution powder mixtures formulated (i.e., mass uniformity test) satisfactory outcomes found content uniformity, disintegration dissolution (with 45 % dissolved after 4 hours). Only friability test unsatisfactory, indicating need improve physical properties powders before compression. These findings open new area developing supplementary dietary. 
 Keywords: Spirulina, Vitamin Matrix tablet, Quality control.
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ژورنال
عنوان ژورنال: Journal of Drug Delivery and Therapeutics
سال: 2023
ISSN: ['2250-1177']
DOI: https://doi.org/10.22270/jddt.v13i9.6202